Pneumonia is a lung disease, and the lungs of a patient with sarcoidosis are greatly weakened by the chronic intraphagocytic metagenomic bacteria that cause the illness. Though it is truly a deadly disease, people don't realize this.
Many are likely convinced by their doctors that sarcoidosis could be successfully kept at bay by high doses of immunosuppressants. People state that their sarcoidosis has “gone into remission". The evidence says that sarcoidosis doesn’t go away. The followed 215 sarcoidosis patients for two years. Two years is the period during which it is sometimes mistakenly thought that the disease can go into remission. NIH ACCESS found that measures of sarcoidosis severity remained unchanged over the two-year period, despite the fact that many patients were using corticosteroids and other immunosuppressive drugs– and despite the fact that the study’s authors went to great lengths to equivocate about what their data really meant.
In fact, in the NIH ACCESS study there were no documented cases of spontaneous remission. Even in the positive-sounding “improved” category for clinical markers, the percentages described were at best “improved”, not “better” and certainly not “cured.” The study also concluded that most patients with persistent sarcoidosis at two years were “unlikely to have resolution of the illness” and that “end-stage pulmonary sarcoidosis usually develops over one or two decades.”
In simple terms, the study found that not one patient recovered over a two year period, and that any patient to remain ill with sarcoidosis for two years is likely to die from the disease over the following ten to twenty years.
Pneumonia is sometimes said to be unrelated to sarcoidosis, but those of us who know better realize that the opposite is true. Many of the chronic bacterial species that cause sarcoidosis create substances that block the Vitamin D Receptor - a fundamental receptor that controls many components of the innate immune response including transcription of the bulk of the body’s antimicrobial peptides.
Our choice to be treated with the “first-line treatment” for sarcoidosis - immunosuppressants including prednisone no doubt - is doubly unfortunate. Doing so inactivates the innate immune system, which allows a heavier load of VDR-dysregulating bacteria to accumulate… which, in turn, further inactivates the innate immune system. In such a state of disrepair, the immune system has little recourse in its fight against an otherwise easily dispatched strain of pneumonia.
Clearly, our doctors incorrectly fault an overactive immune response for the disease. Without being too dramatic, it’s also clear their ignorance has deadly repercussions.
Sarcoidosis is deadly. Also, it is an apt example of how mortality associated with sarcoidosis goes underreported in cases where opportunistic infections are erroneously attributed to be the cause of death. No wonder statistics on sarcoidosis and death are inaccurate. If a patient succumbs to a co-infection directly related to the sarcoidosis disease process the co-infection is blamed rather than sarcoidosis itself.
We can do a service to the community by communicating the actual seriousness of this disease to the public, but instead we make the mistake of accepting the statements of our doctors as an accurate depiction of sarcoidosis
How long will it take before sarcoidosis is given full credit for the deadly disease that it is? The ample use of corticosteroids that weaken immune function - puts patients in a place where they can easily succumb to infections.
Conventional treatment for sarcoidosis is not only ineffective but also quite dangerous and even life threatening.
We also can hope that while tragic, Bernie Mac’s death may at least cause the medical community and the public to raise an eyebrow about the fact that attempts to deny the seriousness of sarcoidosis do little to stop the disease from taking lives. Sarcoidosis Fact Sheet November 2006 Sarcoidosis is a disease that causes inflammation of the body's tissues and is characterized by the presence of granulomas -- small areas of inflamed cells. Sarcoidosis can attack any organ and often affects more than one. However, more than 90 percent of patients with sarcoidosis will have pulmonary involvement.1 Pulmonary sarcoidosis can cause loss of lung volume and increased lung stiffness. For more information call the American Lung Association at 1-800-LUNG-USA (1-800-586-4872).
Sarcoidosis Fact Sheet
Sarcoidosis is a disease that causes inflammation of the body's tissues and is characterized by the presence of granulomas -- small areas of inflamed cells. Sarcoidosis can attack any organ and often affects more than one. However, more than 90 percent of patients with sarcoidosis will have pulmonary involvement.1 Pulmonary sarcoidosis can cause loss of lung volume and increased lung stiffness.
For more information call the American Lung Association at 1-800-LUNG-USA (1-800-586-4872).